Hans Gelderblom Selected Research

Cisplatin (Platino)

1/2022	SLC7A8 coding for LAT2 is associated with early disease progression in osteosarcoma and transports doxorubicin.
1/2022	Genome-wide analyses of platinum-induced ototoxicity in childhood cancer patients: Results of GO-CAT and United Kingdom MAGIC consortia.
1/2019	Ototoxicity in locally advanced head and neck cancer patients treated with induction chemotherapy followed by intermediate or high-dose cisplatin-based chemoradiotherapy.
4/2018	Quality of life of patients with locally advanced head and neck cancer treated with induction chemotherapy followed by cisplatin-containing chemoradiotherapy in the Dutch CONDOR study: a randomized controlled trial.
10/2016	Comparison of MAPIE versus MAP in patients with a poor response to preoperative chemotherapy for newly diagnosed high-grade osteosarcoma (EURAMOS-1): an open-label, international, randomised controlled trial.
5/2016	Replication of a genetic variant in ACYP2 associated with cisplatin-induced hearing loss in patients with osteosarcoma.
7/2015	Methotrexate, Doxorubicin, and Cisplatin (MAP) Plus Maintenance Pegylated Interferon Alfa-2b Versus MAP Alone in Patients With Resectable High-Grade Osteosarcoma and Good Histologic Response to Preoperative MAP: First Results of the EURAMOS-1 Good Response Randomized Controlled Trial.
1/2015	Etoposide and carbo-or cisplatin combination therapy in refractory or relapsed Ewing sarcoma: a large retrospective study.
1/2014	Influence of genetic variants in TPMT and COMT associated with cisplatin induced hearing loss in patients with cancer: two new cohorts and a meta-analysis reveal significant heterogeneity between cohorts.
6/2012	Combination chemotherapy in advanced adrenocortical carcinoma.

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Hans Gelderblom Research Topics

Disease

146	Neoplasms (Cancer) 05/2024 - 01/2002
54	Sarcoma (Soft Tissue Sarcoma) 01/2024 - 07/2008
27	Colorectal Neoplasms (Colorectal Cancer) 01/2024 - 01/2009
24	Gastrointestinal Stromal Tumors (Gastrointestinal Stromal Tumor) 01/2024 - 07/2008
24	Osteosarcoma (Osteogenic Sarcoma) 07/2023 - 04/2011
22	Neoplasm Metastasis (Metastasis) 01/2024 - 09/2005
19	Disease Progression 01/2024 - 06/2012
16	Breast Neoplasms (Breast Cancer) 03/2024 - 06/2003
14	Ewing Sarcoma (Sarcoma, Ewing) 10/2023 - 01/2012
10	Prostatic Neoplasms (Prostate Cancer) 04/2023 - 05/2013
10	Nausea 03/2023 - 02/2011
9	Fatigue 03/2023 - 09/2003
9	Giant Cell Tumor of Tendon Sheath 01/2023 - 03/2012
9	Renal Cell Carcinoma (Grawitz Tumor) 01/2018 - 02/2011
8	Chondrosarcoma 01/2020 - 03/2008
7	Giant Cell Tumors (Giant Cell Tumor) 11/2023 - 06/2015
7	Hypertension (High Blood Pressure) 12/2021 - 06/2008
6	Alopecia (Baldness) 12/2022 - 09/2003
6	Neutropenia 04/2014 - 11/2008
5	Inflammation (Inflammations) 04/2024 - 12/2004
5	Liposarcoma 07/2023 - 01/2014
5	Colonic Neoplasms (Colon Cancer) 01/2023 - 04/2004
5	Vomiting 01/2021 - 02/2011
5	Adrenocortical Carcinoma 01/2021 - 04/2011
5	Giant Cell Tumor of Bone 01/2019 - 01/2016
4	Pain (Aches) 03/2023 - 04/2018
4	Dihydropyrimidine Dehydrogenase Deficiency 01/2022 - 07/2015
4	Ototoxicity 01/2022 - 01/2014
4	Leiomyosarcoma 01/2020 - 01/2016
4	Carcinogenesis 01/2017 - 02/2007
3	Diarrhea 03/2023 - 11/2008
3	Pigmented Villonodular Synovitis 01/2023 - 03/2012
3	Cardiotoxicity 11/2022 - 06/2019
3	Febrile Neutropenia 10/2022 - 04/2014
3	Hearing Loss (Hearing Impairment) 01/2022 - 01/2014
3	Body Weight (Weight, Body) 01/2021 - 08/2010

Drug/Important Bio-Agent (IBA)

26	Tyrosine Kinase InhibitorsIBA 04/2024 - 02/2007
26	Imatinib Mesylate (Gleevec)FDA Link 01/2024 - 12/2007
21	Sunitinib (Sutent)FDA Link 01/2024 - 09/2009
18	Doxorubicin (Adriamycin)FDA LinkGeneric 11/2022 - 03/2012
16	pazopanib FDA Link 12/2021 - 01/2012
14	Biomarkers (Surrogate Marker)IBA 04/2024 - 09/2005
13	Cisplatin (Platino)FDA LinkGeneric 01/2022 - 04/2011
12	Ifosfamide FDA LinkGeneric 10/2022 - 01/2014
10	ripretinibIBA 01/2024 - 01/2020
9	Denosumab FDA Link 11/2023 - 06/2015
9	Irinotecan (Camptosar)FDA LinkGeneric 09/2023 - 11/2005
8	Tamoxifen FDA LinkGeneric 03/2024 - 01/2009
8	Docetaxel (Taxotere)FDA Link 03/2023 - 09/2014
8	pexidartinibIBA 01/2023 - 10/2019
8	Paclitaxel (Taxol)FDA LinkGeneric 08/2022 - 01/2002
8	Oxaliplatin (Eloxatin)FDA LinkGeneric 01/2020 - 03/2009
8	Capecitabine (Xeloda)FDA Link 11/2018 - 03/2009
7	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 01/2009
7	ErbB Receptors (EGF Receptor)IBA 10/2021 - 01/2011
7	Fluorouracil (Carac)FDA LinkGeneric 01/2021 - 04/2004
7	Cetuximab (Erbitux)FDA Link 01/2018 - 07/2010
7	Proteins (Proteins, Gene)FDA Link 01/2018 - 07/2004
6	Bevacizumab (Avastin)FDA Link 04/2024 - 01/2009
6	AnthracyclinesIBA 11/2022 - 04/2016
6	Etoposide (VP 16)FDA LinkGeneric 10/2022 - 06/2012
6	Melphalan (Alkeran)FDA LinkGeneric 01/2022 - 07/2008
5	4-hydroxy-N-desmethyltamoxifenIBA 03/2024 - 11/2013
5	AntibodiesIBA 04/2023 - 09/2011
5	Phosphotransferases (Kinase)IBA 01/2023 - 02/2007
5	Mitotane (Lysodren)FDA Link 01/2021 - 04/2011
5	Cytochrome P-450 CYP2D6 (CYP2D6)IBA 10/2019 - 01/2009
4	Zoledronic Acid (Zometa)FDA Link 10/2023 - 01/2016
4	Cytochrome P-450 CYP3AIBA 01/2023 - 12/2004
4	Vincristine (Oncovin)FDA LinkGeneric 10/2022 - 11/2015
4	Methotrexate (Mexate)FDA LinkGeneric 01/2022 - 07/2015
4	exemestane (Aromasin)FDA Link 01/2021 - 07/2011
4	telatinibIBA 01/2018 - 06/2008
4	Insulin-Like PeptidesIBA 01/2017 - 09/2011
3	Immune Checkpoint InhibitorsIBA 05/2024 - 10/2021
3	AnticoagulantsIBA 10/2023 - 12/2019
3	Messenger RNA (mRNA)IBA 04/2023 - 09/2016
3	Macrophage Colony-Stimulating FactorIBA 01/2023 - 01/2018
3	LigandsIBA 10/2022 - 09/2008
3	Histone Deacetylase InhibitorsIBA 09/2022 - 02/2014
3	UracilIBA 01/2022 - 07/2015
3	Circulating Tumor DNAIBA 12/2021 - 03/2018
3	Estrogens (Estrogen)FDA Link 01/2021 - 07/2011
3	ParaffinIBA 01/2021 - 09/2016
3	Dihydrouracil Dehydrogenase (NADP) (Dihydropyrimidine Dehydrogenase)IBA 01/2021 - 07/2015
3	spartalizumabIBA 01/2021 - 01/2020
3	Formaldehyde (Formol)FDA Link 01/2021 - 09/2016
3	EnzymesIBA 01/2021 - 01/2014
3	Monoclonal AntibodiesIBA 10/2020 - 09/2011
3	Gemcitabine FDA Link 01/2020 - 01/2018

Therapy/Procedure

79	Therapeutics 03/2024 - 12/2004
60	Drug Therapy (Chemotherapy) 04/2023 - 03/2008
19	Radiotherapy 07/2023 - 03/2008
11	Neoadjuvant Therapy 07/2023 - 06/2013
8	Adjuvant Chemotherapy 01/2022 - 02/2010
6	Immunotherapy 05/2024 - 01/2012
6	Aftercare (After-Treatment) 12/2022 - 09/2005
5	Induction Chemotherapy 10/2023 - 07/2015
4	Drug Tapering 01/2020 - 08/2015
4	Castration 01/2020 - 09/2013